Studying stents for coronary artery disease

Results of a large-scale, multicenter study found that treatment with two thin-strut drug-eluting stents were both non-inferior to a durable polymer drug-eluting stent and showed favorable clinical outcomes at one year in treating an all-comers population with a high proportion of patients with acute coronary syndromes….

Results of a large-scale, multicenter study found that treatment with two thin-strut drug-eluting stents were both non-inferior to a durable polymer drug-eluting stent and showed favorable clinical outcomes at one year in treating an all-comers population with a high proportion of patients with acute coronary syndromes….

Dog’s Favorite Toy Comes To Life

We all imagined our favorite toys coming to life when we were younger, right? Jolene’s favorite toy is her Gumby doll, and never in her wildest dreams did she ever imagine that […]

The post Dog’s Favorite Toy Comes To Life appeared first on The Veggie Blog.

We all imagined our favorite toys coming to life when we were younger, right? Jolene’s favorite toy is her Gumby doll, and never in her wildest dreams did she ever imagine that […]

The post Dog’s Favorite Toy Comes To Life appeared first on The Veggie Blog.

Mitochondria control stem cell fate

If the powerhouse of the cell, mitochondria, is disrupted, stem cells in the gut suffer, researchers have discovered. The human intestinal system covers an area of approximately 300 to 500 square meters due to its many protrusions (villi). This inner intestinal wall full of tiny bumps renews itself completely once every four to five days, a process which is guided by stem cells. Mitochondria are the powerhouse of a cell and provide energy through respiration, and play a crucial part in this proc…

If the powerhouse of the cell, mitochondria, is disrupted, stem cells in the gut suffer, researchers have discovered. The human intestinal system covers an area of approximately 300 to 500 square meters due to its many protrusions (villi). This inner intestinal wall full of tiny bumps renews itself completely once every four to five days, a process which is guided by stem cells. Mitochondria are the powerhouse of a cell and provide energy through respiration, and play a crucial part in this proc…

Study yields rich dossier of cancer-linked protein's associates

By developing an atomic-scale picture of how the cancer-linked enzyme PP2A binds to other proteins, researchers have developed a new list of nearly 100 of its potential partners….

By developing an atomic-scale picture of how the cancer-linked enzyme PP2A binds to other proteins, researchers have developed a new list of nearly 100 of its potential partners….

3-D tumors grown in the lab provide new perspective for cancer drug discovery

Understanding how cells within tumors respond to drugs is a critical issue in anticancer drug development. In a new article, researchers report a new approach to study cancer cells’ reactions to treatments and present how it can be used to find new promising drug combinations….

Understanding how cells within tumors respond to drugs is a critical issue in anticancer drug development. In a new article, researchers report a new approach to study cancer cells’ reactions to treatments and present how it can be used to find new promising drug combinations….

Research into basic workings of immune system points to way of improving therapies for cancer

In people with chronic infections or cancer, disease-fighting T cells tend to behave like an overworked militia – wheezing, ill-prepared, tentative – in a state of “exhaustion” that allows disease to persist. In a new paper, researchers have found that in mice with chronic viral infection, exhausted T cells are controlled by a fundamentally different set of molecular circuits than T cells effectively battling infections or cancer — a finding that suggests a way to increase the staying power of …

In people with chronic infections or cancer, disease-fighting T cells tend to behave like an overworked militia – wheezing, ill-prepared, tentative – in a state of “exhaustion” that allows disease to persist. In a new paper, researchers have found that in mice with chronic viral infection, exhausted T cells are controlled by a fundamentally different set of molecular circuits than T cells effectively battling infections or cancer — a finding that suggests a way to increase the staying power of …

Male birth control shots prevent pregnancy

Men can take birth control shots to prevent pregnancy in their female partners, according to a new study. Researchers are still working to perfect the combination of hormonal contraceptives to reduce the risk of mild to moderate side effects, including depression and other mood disorders….

Men can take birth control shots to prevent pregnancy in their female partners, according to a new study. Researchers are still working to perfect the combination of hormonal contraceptives to reduce the risk of mild to moderate side effects, including depression and other mood disorders….

Stability of exhausted T cells limits durability of cancer checkpoint drugs

Reinvigorating exhausted T cells in mice using a PD-L1 blockade caused very few T memory cells to develop. After the blockade, re-invigorated T cells became re-exhausted if antigen from the virus remained high, and failed to become memory T cells when the virus was cleared, report scientists….

Reinvigorating exhausted T cells in mice using a PD-L1 blockade caused very few T memory cells to develop. After the blockade, re-invigorated T cells became re-exhausted if antigen from the virus remained high, and failed to become memory T cells when the virus was cleared, report scientists….

With cancer genome sequencing, be your own control

When a researcher found more than 1,000 genetic translocations in her mouse model of B cell lymphoma, she assumed her lab had made a mistake. To rule out experimental technique as the cause of the way-more-than-expected genomic alterations, the lab sequenced three different types of cells from “wildtype” mice – effectively the kind that might move into your garage in bad weather. Like the lymphoma cells before them, the cells from wildtype mice also had over a 1,000 translocations….

When a researcher found more than 1,000 genetic translocations in her mouse model of B cell lymphoma, she assumed her lab had made a mistake. To rule out experimental technique as the cause of the way-more-than-expected genomic alterations, the lab sequenced three different types of cells from “wildtype” mice – effectively the kind that might move into your garage in bad weather. Like the lymphoma cells before them, the cells from wildtype mice also had over a 1,000 translocations….

Pop-culture news helped destigmatize out-of-wedlock childbirth

Celebrity news reports over the past four decades appear to have contributed to the changing makeup of the traditional American family by helping to destigmatize out-of-wedlock childbirths in the United States, according to a study….

Celebrity news reports over the past four decades appear to have contributed to the changing makeup of the traditional American family by helping to destigmatize out-of-wedlock childbirths in the United States, according to a study….