Drug discovery approach predicts health impact of endocrine-disrupting chemicals

 Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer….

 Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer….

Round or 'shaped' breast implants? Even plastic surgeons can't tell the difference

Looking at before-and-after photos, plastic surgeons and nurses can’t tell whether breast augmentation surgery was done using conventional round implants or newer anatomically shaped implants, reports a new study….

Looking at before-and-after photos, plastic surgeons and nurses can’t tell whether breast augmentation surgery was done using conventional round implants or newer anatomically shaped implants, reports a new study….

Psychiatric conditions linked to increased risk of long-term opioid use

A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications….

A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications….

Anti-aging therapies targeting senescent cells: Facts and fiction

It’s an exciting time to be an elderly mouse. Researchers believe that by removing senescent cells (cells with a persistent damage response), which naturally accumulate with age, senior rodents can regrow hair, run faster, and improve organ function. This strategy may bring us one step closer to the ‘fountain of youth,’ but it’s important to be cautious and not hype, says a researcher of aging….

It’s an exciting time to be an elderly mouse. Researchers believe that by removing senescent cells (cells with a persistent damage response), which naturally accumulate with age, senior rodents can regrow hair, run faster, and improve organ function. This strategy may bring us one step closer to the ‘fountain of youth,’ but it’s important to be cautious and not hype, says a researcher of aging….

Scientists engineer gene pathway to grow brain organoids with surface folding

Researchers provide insight into a specific gene pathway that appears to regulate the growth, structure, and organization of the human cortex. They also demonstrate that 3-D human cerebral organoids can be effective in modeling the molecular, cellular, and anatomical processes of human brain development. And they suggest a new path for identifying the cells affected by Zika virus….

Researchers provide insight into a specific gene pathway that appears to regulate the growth, structure, and organization of the human cortex. They also demonstrate that 3-D human cerebral organoids can be effective in modeling the molecular, cellular, and anatomical processes of human brain development. And they suggest a new path for identifying the cells affected by Zika virus….

Gut microorganisms affect our physiology

Researchers have found evidence that could shed new light on the complex community of trillions of microorganisms living in all our guts, and how they interact with our bodies….

Researchers have found evidence that could shed new light on the complex community of trillions of microorganisms living in all our guts, and how they interact with our bodies….

New tool shines light on protein condensation in living cells

Researchers have unveiled a new tool that uses light to manipulate proteins inside cells, causing liquid-like structures known as membraneless organelles to condense out of a cell’s watery environment. Because these structures play a critical role in cellular operations, and possibly in disease development, the researchers believe the tool will open new areas of cellular biology to exploration….

Researchers have unveiled a new tool that uses light to manipulate proteins inside cells, causing liquid-like structures known as membraneless organelles to condense out of a cell’s watery environment. Because these structures play a critical role in cellular operations, and possibly in disease development, the researchers believe the tool will open new areas of cellular biology to exploration….

The rhythm that makes memories permanent

Every time we learn something new, the memory does not only need to be acquired, it also needs to be stabilized in a process called memory consolidation. Brain waves are considered to play an important role in this process, but the underlying mechanism that dictates their shape and rhythm was still unknown. A study now shows that one of the brain waves important for consolidating memory is dominated by synaptic inhibition….

Every time we learn something new, the memory does not only need to be acquired, it also needs to be stabilized in a process called memory consolidation. Brain waves are considered to play an important role in this process, but the underlying mechanism that dictates their shape and rhythm was still unknown. A study now shows that one of the brain waves important for consolidating memory is dominated by synaptic inhibition….

Role for immune cells in cancer’s ability to evade immunotherapy

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system. One of these escape mechanisms involves a type of immune cell called myeloid-derived suppressor cells (MDSCs). A recent study provides new insight into how MDSCs enable tumor cells to circumvent immune attack and offer the potential for improving cancer immunotherapy….

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system. One of these escape mechanisms involves a type of immune cell called myeloid-derived suppressor cells (MDSCs). A recent study provides new insight into how MDSCs enable tumor cells to circumvent immune attack and offer the potential for improving cancer immunotherapy….