Alzheimer fibrils at atomic resolution

Elongated fibers (fibrils) of the beta-amyloid protein form the typical senile plaques present in the brains of patients with Alzheimer’s disease. A research team has simultaneously succeeded in elucidating the structure of the most disease-relevant beta-amyloid peptide 1-42 fibrils at atomic resolution. This simplifies the targeted search for drugs to treat Alzheimer’s dementia….

Elongated fibers (fibrils) of the beta-amyloid protein form the typical senile plaques present in the brains of patients with Alzheimer’s disease. A research team has simultaneously succeeded in elucidating the structure of the most disease-relevant beta-amyloid peptide 1-42 fibrils at atomic resolution. This simplifies the targeted search for drugs to treat Alzheimer’s dementia….