Alzheimer's researchers find clues to toxic forms of amyloid beta

Much of the research on Alzheimer’s disease has focused on the amyloid beta protein, which clumps together into sticky fibrils that form deposits in the brains of people with the disease. In recent years, attention has turned away from the fibrils themselves to an intermediate stage in the aggregation of amyloid beta. A new study helps lift the veil on the structure and behavior of these neurotoxic ‘oligomers.’…

Much of the research on Alzheimer’s disease has focused on the amyloid beta protein, which clumps together into sticky fibrils that form deposits in the brains of people with the disease. In recent years, attention has turned away from the fibrils themselves to an intermediate stage in the aggregation of amyloid beta. A new study helps lift the veil on the structure and behavior of these neurotoxic ‘oligomers.’…