Chemists develop simple new platform for development of macrolide antibiotics

Researchers have created a new, greatly simplified, platform for antibiotic discovery that may go a long way to solving the crisis of antibiotic resistance. In a study, researchers describe ‘a platform where we assemble eight (chemical) building blocks by a simple process to make macrolide antibiotics’ without using erythromycin, the original macrolide antibiotic, and the drug upon which all others in the class have been based since the early 1950s….

Researchers have created a new, greatly simplified, platform for antibiotic discovery that may go a long way to solving the crisis of antibiotic resistance. In a study, researchers describe ‘a platform where we assemble eight (chemical) building blocks by a simple process to make macrolide antibiotics’ without using erythromycin, the original macrolide antibiotic, and the drug upon which all others in the class have been based since the early 1950s….