Controlling the body clock

A new study investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice. The study shows how this technique was used to quickly create numerous mouse lines, each with different mutations in a circadian regulator called CRY1. Studying each mutation and the effects on behavior showed that specific changes to the protein affected the duration of the circadian period….

A new study investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice. The study shows how this technique was used to quickly create numerous mouse lines, each with different mutations in a circadian regulator called CRY1. Studying each mutation and the effects on behavior showed that specific changes to the protein affected the duration of the circadian period….