Drugs that alter inhibitory targets offer therapeutic strategies for Autism, Schizophrenia

Memories are formed at structures in the brain known as dendritic spines, which communicate with other brain cells through ‘synapses.’ Researchers recently discovered that an inhibitory brain receptor triggers synaptic pruning in adolescence. Now, a new article shows that drugs that selectively target these receptors, when administered during adolescence, can alter synapse number, with possible implications for the treatment of autism and schizophrenia….

Memories are formed at structures in the brain known as dendritic spines, which communicate with other brain cells through ‘synapses.’ Researchers recently discovered that an inhibitory brain receptor triggers synaptic pruning in adolescence. Now, a new article shows that drugs that selectively target these receptors, when administered during adolescence, can alter synapse number, with possible implications for the treatment of autism and schizophrenia….