Mitochondrial dynamics impair nervous system development in Wolfram syndrome

Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics has been less clear. A new study highlights how regulation of mitochondrial turnover is important in the defects of neuronal development that underlie the human genetic disease Wolfram syndrome….

Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics has been less clear. A new study highlights how regulation of mitochondrial turnover is important in the defects of neuronal development that underlie the human genetic disease Wolfram syndrome….