New model of T cell activation

Biologists show that cholesterol prevents an immune response, even when no antigen is present. T cell receptors are an important part of the human immune system. They are able to switch their conformation from an inactive to an active state spontaneously without any antigens present. Cholesterol binds and stabilizes inactive receptors, giving it a decisive role in the activation of a T cell, the study shows….

Biologists show that cholesterol prevents an immune response, even when no antigen is present. T cell receptors are an important part of the human immune system. They are able to switch their conformation from an inactive to an active state spontaneously without any antigens present. Cholesterol binds and stabilizes inactive receptors, giving it a decisive role in the activation of a T cell, the study shows….