Risk factors for congenital heart defects may lie both inside and outside the heart

Congenital heart defects (CHDs) are a leading cause of birth defect-related deaths, but many of the critical genes involved are unknown, and those that are known often contribute only small increases in CHD risk. Researchers report that overall risk is determined by a combination of gene effects both inside and outside of the heart itself….

Congenital heart defects (CHDs) are a leading cause of birth defect-related deaths, but many of the critical genes involved are unknown, and those that are known often contribute only small increases in CHD risk. Researchers report that overall risk is determined by a combination of gene effects both inside and outside of the heart itself….