Scientists identify immunological profiles of people who make powerful HIV antibodies

People living with HIV who naturally produce broadly neutralizing antibodies (bNAbs) that may help suppress the virus have different immunological profiles than people who do not, researchers report. While bNAbs cannot completely clear HIV infections in people who already acquired the virus, scientists believe a successful preventive HIV vaccine must induce bNAbs. Defining how to safely replicate these attributes in HIV-uninfected vaccine recipients may lead to better designed experimental vacci…

People living with HIV who naturally produce broadly neutralizing antibodies (bNAbs) that may help suppress the virus have different immunological profiles than people who do not, researchers report. While bNAbs cannot completely clear HIV infections in people who already acquired the virus, scientists believe a successful preventive HIV vaccine must induce bNAbs. Defining how to safely replicate these attributes in HIV-uninfected vaccine recipients may lead to better designed experimental vacci…