Surprise finding leads to new insights into splenic B cell differentiation

Researchers are familiar with the functions of MZB cells, but the molecular processes involved in their development remained a mystery until an unrelated test revealed that Taok3 plays an essential role. Using these insights, a research team demonstrated that mice genetically lacking in Taok3 did not develop MZB cells, and are more susceptible to bacterial infection….

Researchers are familiar with the functions of MZB cells, but the molecular processes involved in their development remained a mystery until an unrelated test revealed that Taok3 plays an essential role. Using these insights, a research team demonstrated that mice genetically lacking in Taok3 did not develop MZB cells, and are more susceptible to bacterial infection….