Tamoxifen resistance linked to high estrogen levels in utero

Resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals, research in animal studies suggests. This study provides a new path forward in human research as about half of the breast cancers treated with this common cancer therapy do not respond well, say researchers….

Resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals, research in animal studies suggests. This study provides a new path forward in human research as about half of the breast cancers treated with this common cancer therapy do not respond well, say researchers….