Uncovering a 'smoking gun' in age-related disease

Aging is a key risk factor for a variety of devastating, chronic diseases, yet the biological factors that influence when and how rapidly cells deteriorate over time remain largely unknown. Now, for the first time, a research team has linked the function of a core component of cells’ machinery — which cuts and rejoins RNA molecules in a process known as “RNA splicing” — with longevity in the roundworm. The finding sheds light on the biological role of splicing in lifespan and suggests that man…

Aging is a key risk factor for a variety of devastating, chronic diseases, yet the biological factors that influence when and how rapidly cells deteriorate over time remain largely unknown. Now, for the first time, a research team has linked the function of a core component of cells’ machinery — which cuts and rejoins RNA molecules in a process known as “RNA splicing” — with longevity in the roundworm. The finding sheds light on the biological role of splicing in lifespan and suggests that man…