Engineered human colon model could aid in cancer research

A multi-institution collaboration has published research on a tissue-engineering method that allows forward genetics screening on human tissue. The team created a human colon model by first deleting cells from normal human colon tissue, while retaining most of the molecules to which the cells adhere. The tissue is then repopulated with cells obtained from colonoscopy patient samples and from commercial sources….

A multi-institution collaboration has published research on a tissue-engineering method that allows forward genetics screening on human tissue. The team created a human colon model by first deleting cells from normal human colon tissue, while retaining most of the molecules to which the cells adhere. The tissue is then repopulated with cells obtained from colonoscopy patient samples and from commercial sources….