Nanodiscs catch misfolding proteins red-handed

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level….

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level….