Pulmonary fibrosis caused by single transcription factor

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease. In research on mice, the progress of the disease was able to be halted using drugs that boost FoxO3 activity. The researchers are hoping they may have found a possible approach to treatment….

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease. In research on mice, the progress of the disease was able to be halted using drugs that boost FoxO3 activity. The researchers are hoping they may have found a possible approach to treatment….